对于中药毒性的深入研究和正确认识,解决既充分发挥有毒中药疗效,又能最大限度地降低毒副反应的矛盾,建立一套完整的国际中药安全评价标准,是加快中药现代化国际化进程的重要任务。本文概要地回顾了毒性中药研究历史和研究方法,提出要在总结前人宝贵经验的基础上,走出毒性中药的认识误区,运用现代药理学、毒理学知识,通过先进的实验手段进行中药毒理学研究。

As for the deep study and correct understanding of the toxicity of Chinese herbal medicines, should be well handled the contradiction that not only the curative effectiveness of poisonous medicines should be brought into full play, but also their toxic reaction and side-effects should be reduced to the minimum so as to establish a set of complete world criteria for the assessment of the safety of Chinese medicines, and this is an important task for the acceleration of the modernization and internationalization of Chinese medicines. This article generally reviews the history and methods of the study on poisonous Chinese medicines and proposes that people should get out of the misunderstanding of poisonous Chinese medicines on the basis of summing up the valuable experience of our predecessors, and cany out the study on the toxicology of Chinese herbal medicines by making use of the knowledge of modern pharmacology and toxicology and advanced experimental means.

国家中医药管理局专项基金(02-03ZP29)