本文从中药缓释剂的药代动力学研究在中药现代化中的作用出发,以肝苏缓释胶囊的药代动力学研究为例,对中药缓释剂药代动力学的方法进行分析和评价,总结各自的优缺点。并根据大量文献资料及作者在肝苏缓释胶囊药代动力学研究过程中的体会,对中药缓释剂动力学研究的难点及发展趋势进行分析和概括。中药缓释剂药代动力学的研究还处于探索阶段,其理论及技术体系的创新,必将随着科学技术的发展进一步规范和成熟。

Starting from the role of the study on the pharmacokinetics of slow releasing drugs of traditional Chinese medicine （TCM） in the modernization of TCM and taking the study on the pharmacokinetics of the slow releasing capsule for liver as an example, this article analyzes and assesses the method for the pharmacokinetics of slow releasing drugs of TCM and summarizes its merits and defects. In the article the authors analyze and epitomize the difficulties and tendency of the study on the pharmacokinetics of slow releasing drugs of TCM on the basis of large quantities of literatures and materials and in accordance with the authors' experience in their study on the pharmacokinetics of the slow releasing capsule for liver. The study on the pharmacokinetics of slow releasing drugs of TCM is still in the exploratory period, but its theory and technical system are bound to be further normalized and grow ripe with the development of science and technology and then push ahead the modernization and internationalization of TCM.

国家“十五”攻关计划课题(2001BA701A07-17)