目的:制备五倍子鞣酸精制品（对照品）及制定质量标准。方法:应用大孔高分子吸附树脂精制五倍子鞣酸;采用HPLC及LC/MS图谱研究五倍子鞣酸精制品的质量。结果:五倍子鞣酸精制品含量≥98%,没食子酸含量<0.2%,具稳定的HPLC特征图谱。精制收得率64%。并制定相应的质量标准。结论:以大孔高分子吸附树脂精制五倍子鞣酸可作为鞣酸含量测定法（中国药典2000年版一部附录XB）的替代法的对照品应用。

Objective:To prepare purified products （reference substances） of tannin from Galla Chinensis and formulate their quality standards. Method: To prepare tannin from Galla Chinensis with macropore high molecular absorption resin and analyze the quality of the purified tannin by HPLC method and LC/MC spectra. Result: The purified tannin product obtained from Galla Chinensis contains NLT 98% of tannic acid and less than 0. 2% of gallic acid, and has stable HPLC characteristic spectrum. The yield of purification processing is 64% and relevant quality standards are formulated. Conclusion: Tannin prepared with macropore high molecular absorption resin can be used as reference substance in the substitution method of tannin assay （Appendix XB, Volume I, CP2000）.

国家中医药管理局科学技术研究专项课题(02-03ZL11):鞣质含量测定法(中国药典2000版一部)的替代法研究