本文采用组分中药的研究模式,以发展构建中药组分库为核心, 选取葛根为研究对象, 探讨了组分的分离与表征方法。应用工业色谱及相关技术,发展了高效的规模组分制备分离方法,获取了18个正丁醇部位的制备组分。利用高效液相色谱,获取了 18个组分化学指纹谱,与标准品对照,对组分进行了初步表征。

In this study TCM components are taken for its model, the construction and development of TCM component library are regarded as its core and the root of kudzu is chosen as its object to explore the method for the separation and characterization of TCM components. As a result a method for efficient preparation and separation of scale components has been developed and 18 components from n-butyl alcohol fraction have been obtained due to the application of industrial chromatograph and other related techniques, and 18 fingerprints of component chemistry have been achieved by HPLC, which have been preliminarily characterized via comparison of them with standard ones.

国家自然科学基金重点项目(20235020)：中药药效组分指纹图谱分析方法的研究,负责人:梁逸曾；中国科学院知识创新工程重要方向项目(KGCX2-SW-213)：基于现代理论和技术的复方中药系统研究,负责人:梁鑫淼。