[关键词]
[摘要]
由于脑核团功能有所不同,因此药物在不同核团的分布则对其药理作用产生一定的影响。对于药物脑核团分布动力学进行观察,将有助于更好的了解药物调节脑功能的作用,同时也为临床合理用药提供有价值的实验数据。对于具有复杂体系特点的中药来说,更是如此。
[Key word]
[Abstract]
Due to different functions of cerebral nuclei,the pharmacological effects could be affected while the drugs dis- tribute in different nuclei.Studying the kinetic behavior of drugs will help discover the impact of drugs in modulating brain function and provide significant data for rational clinical using of drugs,especially for the Chinese herbs which are quite complex.
[中图分类号]
[基金项目]
清华大学基础科学基金(JC2001061):中药复方药代动力学的方法学研究;; 北京科技攻关项目(No．Z0004 105 040311):先导物和中药的ADMET性质快速集成评价实验平台
