目的：系统综述循证医学在中医药国际化中的应用。方法：本文综述了中医药和循证医学研究两方面的特点、定位、吻合度,循证医学推动中医药国际化的基本形式和基本情况,已开展的中医药应用循证医学研究工作,目前中医药循证医学研究取得的结果,存在的问题与挑战。结果：在推进中医药国际化的循证医学研究组织建构,国家立项支持开展的安全性、有效性评价研究,中医药科学评价体系的建立,中医中药系统评价、教育、人才培养及发表论文、获得成果方面取得了很大成绩。结论：中医药国际化的关键是临床疗效的肯定,倡导参照循证医学评价方法,建立反映中医药“整体调节”优势的复杂、多维的终点指标评价体系。

Objective:Systemically summarize studies on application of evidence based medicine (EBM) in internationalization of Traditional Chinese Medicine (TCM).Methods:Our article summarize the characteristic, orientation and accordance between TCM and EBM,basic form and basic information on EBM in proposing internationalization of TCM,application of EBM in TCM,achievement,existing problem and challenge of EBM. Results:Achievements have attained on organization of EBM,country-sustained study on evaluation of security and validity,establishment of scientific evaluating system,systematic review of TCM,education and talent cultivation, published article and production.Results:The key of internationalization of TCM is the affirmation of effects,it is proposed to establish complex,multidimensional endpoints outcome evaluation system which can reflect the advantage of whole regulation referring to EBM evaluation methods.