[关键词]
[摘要]
本研究通过对多种现代分离技术的集成,构建了中药系统分离制备的标准化平台,并制定了一系列标准操作规范控制提取分离过程。通过平台运行,已完成了50味中药和8个复方的1100多个标准组分的分离制备,建立了一定规模的标准组分库和相应的标准操作规范。初步形成了中药标准组分库,为中药物质基础研究和创新中药研发提供了丰富的组分资源。
[Key word]
[Abstract]
A systematic and standard platform for separation and preparation of Traditional Chinese Medicine has been con- structed by integration of multiple modern separation technologies.A series of standard operation protocols (SOPs) was carried out to control the extraction and separation procedures.50 Chinese herbs and 8 prescriptions have been pro- cessed with this system,and more than 1100 standard multi-components have been produced.A library for standard multi-components of Traditional Chinese Medicines has been formed,which provides abundant multi-components for chemical constitution research and new medicine development.
[中图分类号]
[基金项目]
中国科学院知识创新工程重要方向项目(KGCX2-SW-213)基于现代理论和技术的复方中药系统研究;; 国家自然科学基金重点项目(20235020)中药药效组分的指纹图谱分析的方法研究