[关键词]
[摘要]
天然产物高压差提取分离浓缩器的核心技术在于多级膜与高压差提取器的联用设计.它是通过合理的结构设计、流程与自控设计以及排污和安装设计,将高压差提取、微滤澄清、超滤分离、纳滤或反渗透浓缩、在线清洗、过程自控等多技术单元进行组合,形成完整的技术及成套装备,可较好地实现中药提取物全过程低温(20℃以下)制备,达到洁净区流程化生产的目的.
[Key word]
[Abstract]
The core technique of the high-pressure differential extraction, separation and concentration equipment for natural products is the design of multi-level membrane and high-pressure differential extraction in combination. Based on the rational structrul design, process and automation design, as well as sewerage and installation design, this technique makes up various technical steps, including high-pressure differential extraction, microfiltration clarification, ultrafiltration, nonofiltration or reverse osmosis concentraion, on-line cleaning process, and procedure auto control technique, thus forming a complete set of techniques and equipments. This makes it possible to prepare the traditional Chinese medicine extract at low temperature (20 ℃ or less) during the entire process, thus fulfilling the scheduled production in a clean area.
[中图分类号]
[基金项目]
国家科技部等14个部委和广东省人民政府共同主办的"2009'传统医药国际科技大会暨博览会"同期活动五--"现代中药制药装备研究开发论坛"推荐论文;国家科技型中小企业技术创新基金无偿资助项目(07C26214401795):连续式高效低温提取浓缩器的应用开发研究,负责人:宋力飞;国家科技部支撑计划子课题(2006BAI06A04-01):中药现代提取分离关键技术及装,负责人:葛发欢,刘乡乡;广东省技术创新项目(200872203):全自动中药低温提取分离浓缩器的开发应用,负责人:宋力飞;广东省科技厅粤港关键领域重点突破项目(2009498C1402):模块化集装箱式提取分离浓缩器的研究,负责人:宋力飞。