目的:研究益肾蠲痹法治疗系统性红斑狼疮的疗效.方法:本研究应用"益肾蠲痹法"对54例曾用激素或免疫抑制剂治疗系统性红斑狼疮,因副作用而改用益肾蠲痹法治疗3年以上的患者,观察治疗前后临床疗效、症状积分、激素剂量、血沉、C反应蛋白、ENA系列等指标变化.结果:54例系统性红斑狼疮患者治疗后的症状积分显著下降,ESR、CRP明显下降;激素用量逐渐撤减至停服,ENA系列指标阴转率最高达96.3%.结论:益肾蠲痹法对难治性系统性红斑狼疮,具有疗效高、毒副作用小、症状及实验室指标改善明显等理想疗效,是一种易于推广使用、具有良好产业化前景的治疗方法.

This study aimed to study the character of tongue demonstration of suffering from excessive internal heat. The tongue demonstration of 303 cases suffering from excessive internal heat was observed with naked eyes by doctors and recorded in an observation table. At the same time, 145 healthy cases were taken as the control group. The chi-square test and partial correlation analysis showed that the character of tongue demonstration of suffering from excessive internal heat manifested red tongue, increased prickles on the tongue tip, thick fur, light yellow fur and dry fur. Suffering from excessive internal heat is one kind of pyretic syndrome which makes an important content of preventative medicine and follows the prognosis of a disease in TCM. The understanding of the character of tongue demonstration and the time series rule of occurrence will conduce to normative diagnosis and evaluation of the interventional effect of suffering from internal heat.

国家科学技术部等14部委和广东省人民政府共同主办的“2009’传统医药国际科技大会暨博览会”第四分会——“传统医药的继承、创新及其方法学”论文，该论文为大会学术委员会评选的优秀论文；国家中医药管理局2005年全国中医药科技成果推广项目[国中医药办发（2005）30号]：益肾蠲痹法治疗风湿病，负责人：朱婉华。