目的：探讨种质和产地环境对刺五加药材质量的影响。方法：将我国东北11个不同产区种质种植在同一产地、同一产地种质种植11个不同产地，采用高效液相色谱法以刺五加苷B和刺五加苷E的含量为指标评价不同刺五加药材质量。结果：同产地不同种群的种质对刺五加药材质量的影响较大，而不同产地种质对药材质量影响较小；刺五加质量受环境影响较大，存在适宜产地的边缘效应。结论：在黑龙江省北部和辽宁省南部山区种植刺五加在某种程度上可提高药材质量。

This work aimed to explore the effect of different germplasms and production environments on the medicinal material quality of Acanthopanax senticosus. Acanthopanax senticosus seedlings originated from 26 populations grown in 11 different production zones of Northeast China were cultivated in the same place, while the same seedlings were cultivated in 11 different growing areas. The HPLC method was used for determining the eleutheroside B and eleutheroside E contents in roots and stems. The germplasms of different populations had greater impact on the quality of crude drugs than the production environment. The environment of different production zones influenced the quality of crude drugs because of the edge effect of origins. Taken together, cultivation of Acanthopanax senticosus in the northern part of Heilongjiang and Liaoning provinces may improve the quality of this medicinal herb.

科学技术部“十一五”国家科技支撑计划子课题（2006BAI09B02-07）：道地药材生态适宜性分析技术研究，负责人：孟祥才。