心力衰竭（HF）中医证候学研究是实现病证结合、方证对应的关键。HF证候演变起于阴阳之变，终于阴阳衰竭，不离五脏，又以心肾为中心，就此提出阴阳五脏论的演变假说。HF证候规范化亟待解决，而方法学的应用将为证候标准的建立与使用带来希望。

TCM syndromes of heart failure (HF) are considered the key to realize integration of diseases with differentiation of their syndromes，as well as the correspondence between recipes and syndromes. The evolution of HF syndromes starts with changing of yin-yang and ends with collapsing of yin-yang. This process depends on five visceras，the center of which is the heart and kidney. Then we present a hypothesis of yin-yang and five visceras on the evolution of HF syndromes. Standardization of HF syndromes is urgently needed，while methodology sheds light on the establishment and usage of standardization of HF syndromes in future. Objective syndromes of HF may lead to the discovery of the syndromes essence，which relies on case-based TCM evidence via integration of modern science and technology.

首都医学发展科研基金项目（SF2007I04）：参附注射液治疗心力衰竭临床疗效评价及对骨髓干细胞动员作用研究，负责人：王阶。