[关键词]
[摘要]
转化医学是将基础生物医药的成果和技术快速转化并应用到疾病的预防、诊断和治疗,基础与临床双向互动(BtoB)的一门新学科。中药是我国的特色、优势产业,正处于从传统中药经过中药现代化到创新中药的发展阶段,继承与创新、基础与临床相结合是创新中药的核心思想。这与转化医学BtoB 的研究模式关系十分密切。在这个转化过程中,充分利用中医药理论指导的优势和中药整体调节的特色,探求还原与整合结合的思路和方法对于中药新药创制具有积极的推动作用。
[Key word]
[Abstract]
Translational medicine is a new subject that focuses on the transition process of developing and delivering basic theoretical and technological tools to assist prevention, diagnosis, and treatment of diseases. Translational medicine is regarded as a double-way route: Bench to Bedside and Bedside to Bench (BtoB). Traditional Chinese medicine (TCM), as a predominant industry in China, is undergoing the modernized progress from traditional Chinese herbs to Chinese medicine innovation. During the process, inheritance and innovation of TCM as well as the combination of basic research and clinical research are emphasized. The concept of inheritance, innovation and combination is closely related to the BtoB mode of translational medicine. Guided by TCM theories and characteristics of integrated multi-component regulation, the strategy of combining reduction with integration will further promote the modernization of TCM and new drug innovation.
[中图分类号]
[基金项目]
中科院知识创新重要方向性项目(KSCX2-YW-R-078):具有雌激素作用中药复方物质基础及作用机理研究,负责人:肖红斌。