目的:从脉诊角度研究亚健康状态脉弦的客观化指标。方法:选择亚健康状态脉弦人群为研究对象,将其分别与高血压脉弦及健康状态脉弦两组人群对比,切脉后,用BD-SZ型四诊合参辅助治疗仪同步采取正常脉图、二导心电图,分析手感特征、脉图特征及脉图参数。结果:健康状态、亚健康状态、高血压状态脉弦指下感觉依次增强,脉图特征渐失柔和,亚健康组脉图参数介于健康状态组和高血压组之间。主波宽(TW)逐渐增大;降中波/主波高(HFF/HB)比值逐渐降低;降中峡高/主波高(HE/HB)比值逐渐升高;脉搏波传导速度(TAG)逐渐增大;与健康组和高血压组相比均有显著差异(P<0.05)。主波高(HB)、升支斜率(Sup)、主波时间(TAE)逐渐增大,与健康组和高血压组相比无显著差异(P>0.05),但高血压组与健康组相比有显著差异(P<0.05)。结论:亚健康状态脉弦脉图变化介于健康状态和高血压脉弦之间,可以通过客观化手段对其进行评价,进一步分析其他脉图的亚健康状态特征,为最终建立起亚健康状态的中医四诊客观化体系奠定基础。

Wiry pulse in sub-health state was studied based on the perspective of objective pulse diagnosis.Sub-health wiry pulse was selected as study group and hypertension wiry pulse and health state wiry pulse was included as comparison.The position of pulse was located and the pulse was felt by doctor.Then the NX-8 multifunctional sphygmograph machine was applied to take pressure sphygmogram and ECGⅡ synchronizedly.Indexes,such as Height of B wave(HB),Mean Slope up(Sup),Mean Slope down(Sdown),Time between point A and E wave(TW),Time of Slope up / Pulse rate,and Time of Bwave(TB),were recorded.The results showed that the pulse strength is felt gradually increased from health state,sub-health state to hypertension by hand.The sphygmogram changed in TW,HFF/HB,HE/HB,TAG compared with the value of sub-health state and hypertension group(P<0.05).The pressure sphygmogram of wiry pulse in sub-health state can be objectively valued between the health state and the hypertension group.More parameter of sphygmogram in sub-health state should be studied.The study of wiry pulse has laid a foundation in objective study of sub-health state by traditional Chinese medicine.

国家自然科学基金面上项目(30371720):中医脉诊属性的检测技术与方法探讨,负责人:牛欣;国家自然科学基金重点项目(60431020):中医关键诊断信息获取与处理理论的技术研究。负责人:牛欣;科学技术部国家“十五”科技攻关计划项目(2004BA721A09):中医脉象信息采集关键技术研究。负责人:牛欣;科学技术部国家“十一五”科技支撑计划项目(2007BAI07A23):便携式辅助诊疗设备开发和导航针刀应用技术开发。负责人:杨学智;2010年度北京市丰台区卫生系统科研项目(201000093):西罗园社区亚健康人群健康管理平台的建立。负责人:董晓英;2009年度北京市丰台区科技新型计划支持项目:西罗园社区亚健康人群健康管理平台的建立,负责人:董晓英