针对野生菌种在人工培养基上容易丢失产生子实体的能力，稳定性差，且野生型菌种虫草菌素等生理活性物质含量较低等影响北虫草规模化人工栽培的问题，本文探索利用紫外线对出发菌株P进行诱变处理，以生物转化率、虫草素、腺苷含量为指标，筛选出高产菌株89，其有性子实体中虫草素含量和腺苷含量分别是出发菌株的2.5倍和3.6倍。进一步对其进行传代稳定性试验测试后，可用于大规模工厂化北虫草培育用菌种。

Based on problems existed in the cultivation of Cordyceps militaris (L.) strain, ultraviolet ray was used to mutate original thallus P. Biological conversion rate, content of cordycepin and adenosine were evaluated as indexes. The amount of screened high output strain was 89. The content of cordycepin and adenosine were 2.5 times and 3.6 times than before, respectively. Genetic stability experiments indicated the strains were stable and can be used as parent thallus in large-scale.

科学技术部“十一五”国家863计划重点项目（2007AA021502）：北虫草人工替代品规模化生产关键技术，负责人：唐亮。