目的：制备补阳还五单室渗透泵缓释片，并考察其主要有效成分“整体受控、同步释放”的情况。方法：指纹图谱相似度评价。结果：制备了补阳还五单室渗透泵缓释片，并获得了其体外释放的指纹图谱及其成分的体外释放同步性的数据。结论：补阳还五单室渗透泵缓释片能够做到多种成分整体受控，符合中药复方用药的特点。

The study was aimed to prepare Bu-Yang-Huan-Wu(BYHW) elementary osmotic pump sustained release tablets and investigate the situation of its main effective components of "synchronous control and sustained release." Release similarity of chromatographic finger prints of BYHW in vitro dissolution was evaluated. The results showed that BYHW elementary osmotic pump sustained-release tablet was prepared and the chromatographic finger prints were extracted. And data of its release similarity was also obtained. It was concluded that BYHW elementary osmotic pump sustained-release tablet can achieve the synchronous control and sustained release of many ingredient. It is also fit for the characteristic of Chinese herbal medicine compound.

国家自然科学基金项目（81073142）：中药复方有效性数学模型的建立及对补阳还五汤的研究，负责人：贺福元；国家自然科学基金项目（81173558）：中药复方成分群提取过程动态迁移与稳态性规律的研究，负责人：罗杰英；长沙市科技局科技计划项目（K1109035-31）：中药多成分整体同步受控缓控释制剂制备与应用研究，负责人：杨岩涛。