目的：探索矩阵分析法在中医辨证论治疗效评价中的应用。方法：以慢性萎缩性胃炎（CAG）为范例，临床选择经“虚实标本证候辨识数据库”辨识的CAG 5种虚实相兼证候共100例，采用补虚泻实、标本兼治的证治方法治疗，半年为一疗程，疗程结束后采用证候矩阵、治疗矩阵、效果矩阵模型的变量测算及误差矩阵推导，推算出疗效值。结果：虚实标本辨治慢性萎缩性胃炎总体症状的疗效为0.4~0.6，具有统计学意义（P<0.05）。结论：初步表明矩阵分析法可用于中医辨证论治的疗效评价。

This study was aimed to explore the application of matrix analysis method in the effectiveness assessment of syndrome differentiation and treatment. A total of 100 chronic atrophic gastritis (CAG) cases were selected randomly from the Database of Deficiency-Excess and Branch-Root Syndrome Differentiation set up by the teamwork. All patients were classified into five syndrome differentiation patterns and treated from both the root and the branch of CAG with the treatment principle of nourishing the deficiency and reducing the excess. The treatment course was half a year. When the treatment course completed, the effectiveness value was calculated based on the variable measurement and error matrix of syndrome matrix, treatment matrix and effectiveness matrix model. The results showed that the effectiveness value of syndrome differentiation and treatment in improving CAG symptoms is between 0.4 and 0.6. It has statistical difference(P<0.05). It is concluded that the preliminary study showed that the matrix analysis method can be used for traditional Chinese medicine syndrome differentiation and treatment effectiveness assessment.

国家自然科学基金项目（30873266）：基于慢性萎缩性胃炎癌前病变虚实关联证候辨治的临床疗效评价方法研究，负责人：沈舒文；国家中医药管理局陕西中医学院附属医院脾胃病重点学科，学科带头人：沈舒文。