目的：对上海地区健康人群四季面色变化进行量化客观化研究。方法：应用舌面一体检测系统，观察上海地区健康人群四季面色特征。结果：四季面色R、G、B值结果显示G-B值秋季稍高，秋季与冬季G-B值有统计学意义（P<0.05），说明秋天面色偏于黄色；L、a、b值结果显示夏季a值最高，夏季与春季a值存在显著性差异（P<0.001），夏季与秋季a值存在显著性差异（P<0.001），说明夏季面色以红色为特点；b值春季较高，春季与夏季b值存在显著性差异（P<0.001），春季与冬季b值存在显著性差异（P＜0.01），提示春天面色偏青；冬季面色L值最低，冬季与秋季L值有统计学意义（P<0.05），提示冬季面色较暗，面色偏于灰黑色。结论：证实面色随季节更替是存在一定规律变化的，且以客观测量和定量分析方法验证了中医学认为“人体面部色泽四季之间有一定变化”的理论。

This study was aimed to conduct objective quantitative analysis on facial complexion in four seasons among healthy people in Shanghai. The Tongue-Complexion Detection System (TCDS) was used in the observation of facial complexion features in four seasons. The results showed the RGB values of normal facial complexion in four seasons of Shanghai. In autumn, GB values are slightly high. There is statistical significance on GB values between autumn and winter (P<0.05). It showed that in autumn the facial complexion is more yellow. The L, a, b values of the results showed that in summer the a value is the highest. There is significant difference on a value between summer and spring (P<0.001). There is significant difference on a value between summer and autumn (P<0.001). It showed that in summer the feature of facial complexion is red. The b value is relatively high in spring. There is significant difference on b value between spring and summer (P< 0.001). There is significant difference on b value between spring and winter (P<0.01). It showed that the facial complexion in spring is greenish. The L value of facial complexion in winter is the lowest. There is significant difference on L value between winter and autumn (P<0.05). It showed that the facial complexion in winter is darker. The facial complexion is more grey and black. This study proved that there were certain principles on the change of facial complexion corresponding to seasons. This objective quantitative analysis verified the traditional Chinese medicine theory that "one's facial complexion changes according to four seasons".

上海市科委择优委托项目（09DZ19079028）：中医四诊检测系统临床应用研究，负责人：王忆勤；上海市教委第三期中医诊断学重点学科经费资助项目（J50304）：负责人：王忆勤；海南省自然基金资助项目（811205）：海南美登木对人肝癌HepG2细胞增殖及凋亡相关因子表达的影响，负责人：宫爱民。