目的：基于Discovery Studio 软件研究五味子乙素的质谱裂解机制。方法：在正离子模式，用线性离子阱质谱得到五味子乙素的质谱图。结果：通过Discovery Studio 解析五味子乙素多级质谱碎片，主要发生环的开裂，H2O，-CH3 和-OCH3 等自由基丢失。结论：本研究丰富五味子乙素的质谱裂解机制，为木脂素类成分的结构鉴定研究提供依据。

This study was aimed to find the fragmentation pathways of Schisandrin B using the Discovery Studio by electrospray ionization mass spectrometry (ESI-MSn). The first and multi-stage mass spectrum diagrams were obtained. The results showed that mass spectrometry fragments of Schisandrin B was analyzed under the positive mode, the cracking rings are mainly occurred, and free radicals such as H2O, -CH3 and -OCH3 were lost. It was concluded that this study enriched the mass spectral decomposition, and provided basis for the study on chemical constituents of lignan compounds.

国家自然科学基金委青年基金项目（30901959）：基于质谱裂解规律和量子化学预测乌头碱代谢规律研究，负责人：刘永刚。