[关键词]
[摘要]
目的:应用中医传承辅助系统软件分析黄春林教授治疗肾病综合征(NS)的用药及组方规律。方法:收集黄春林教授治疗NS 病例,录入“中医传承辅助平台”系统,采用系统中的关联规则、改进互信息法、复杂系统熵聚类等无监督数据挖掘方法,总结黄教授治疗NS 的常用药物及分析方剂中的组方规律。结果:对纳入的68 名患者病例,共280 张处方进行分析,确定处方中药物的使用频次,药物间的关联,挖掘黄春林教授治疗NS 的基本方及8 首新处方。结论:数据挖掘法对于挖掘名老中医临床经验具有重要实用价值。
[Key word]
[Abstract]
This study was aimed to analyze the medication and herbal prescription rules in the treatment of nephrotic syndrome (NS) by Prof. Huang Chunlin with Traditional Chinese Medicine Inheritance Support System (TCMISS). Prescriptions used for NS treatment were collected and the data was entered into the TCMISS. The commonly used herbs and herbal prescription rules in NS treatment by Prof. Huang were summarized through the association rules, revised mutual information, complex system entropy cluster and other unsupervised hierarchical clustering methods. The results showed that based on the analysis of 280 prescriptions from 68 patients, the frequency of each herb and association rules among herbs included in the database were identified. And the basic NS treatment prescription by Prof. Huang Chunlin and 8 new prescriptions were mined from the database. It was concluded that data mining is of great practical value to the summarization of clinical experiences of well-known TCM doctors.
[中图分类号]
[基金项目]
国家中医药管理局2011 年全国名老中医传承工作室建设项目(2012KT1301):黄春林全国名老中医药专家传承工作室,负责人:刘旭生;国家中医药管理局中医临床研究基地业务建设科研专项,负责人:刘旭生。