[关键词]
[摘要]
目的:基于中医传承辅助系统软件分析黄春林教授治疗慢性肾脏病(CKD)用药特点。方法:收集黄春林教授治疗CKD 病例,采用关联规则、复杂系统熵聚类等无监督数据挖掘方法,确定处方中各种药物的使用频次及药物之间的关联规则,分析黄春林教授治疗CKD 的用药经验。结果:对纳入63 份病例,226 张处方进行分析,确定病例中常见症状,处方中药物使用频次,药物间关联,挖掘黄春林教授治疗CKD 用药特点。结论:黄春林教授以健脾补肾法为基本治法,选用黄芪、杜仲、仙灵脾、菟丝子、藿香、丹参、女贞子辨病辨证相结合,治疗CKD 经验丰富。中医传承辅助系统对于挖掘名老中医临床经验具有重要实用价值。
[Key word]
[Abstract]
This study was aimed to analyze the formulas and classify the treatment of chronic kidney disease(CKD) by Dr. Huang Chunlin based on the data mining method. A total of 63 CKD outpatients' medical records by Dr. Huang were collected. And 226 formulas prescribed in the medical records were put in the Traditional Chinese Medicine Inheritance Support System (TCMISS). Data mining techniques were applied in the study of association rule mining algorithm and complex system entropy cluster, the usage frequency and the correlation of each single Chinese medicinal in order to sort out the prescription pattern of CKD. The results showed that to fortify the spleen and tonify the kidney were found to be the basic method of CKD treatment. Through the application of TCMISS, the Chinese medicinals used in Dr. Huang's CKD treatment were Astragalus root, Eucommia,Epimedium, Cuscuta, Agastache, Danshen Root, Ligustrum. It was concluded that the TCMISS is of great value in the summarization of clinical experiences of well-known TCM doctors.
[中图分类号]
[基金项目]
国家中医药管理局2011 年全国名老中医传承工作室建设项目(2012KT1301):黄春林全国名老中医药专家传承工作室,负责人:刘旭生;国家中医药管理局中医临床研究基地业务建设科研专项,负责人:刘旭生。