慢性肾衰竭（CRF）是一种进展性的疾病，病理损伤形成后很难逆转，需采用多种方法进行综合治疗，且需终身治疗与调理。本文提出CRF 在治疗上应根据病情的不同发展阶段，采用相应的治疗措施，早、中期以延缓CRF 进展为目的，采用中医综合治疗；尿毒症期需在肾替代治疗的基础上，降低透析或减少肾移植并发症的产生，提高生存质量。从中医汤剂的辨证论治的角度、中医外治以及具有中医特色的慢性肾脏病管理等3 个方面着手对CRF 进行一体化治疗，才能取得较好的治疗效果。

Chronic renal failure (CRF), which is a progressive disease, is difficult to be reversed after the pathological damage was formed. Hence, a variety of integrated and complementary therapies should be used for the lifelong treatment and regulation. This article suggested that therapeutic methods should be given according to different stages of CRF in its development. Chinese medicine comprehensive therapy should be given to the early and middle stage chronic renal failure patients in order to delay the disease progression. In the uremia stage, replacement therapy should also be used as the basic treatment in order to reduce the general complications of dialysis or a kidney transplant, thereby improving the quality of life of patients. The integration of Chinese medicine therapy on CRF are from three aspects, which are Chinese medicine decoction based on syndrome differentiation, Chinese medicine external therapy and Chinese medicine featured CRF management in order to receive better therapeutic effects.

国家中医药管理局中医药行业科研专项（201007005）：慢性肾炎蛋白尿和慢性肾脏病4 期中医治疗方案验证和推广应用研究，负责人：刘旭生、杨霓芝、何立群。