黄褐斑是一种多见于中青年女性面部的色素沉着性皮肤病，以面部曝光部位发生获得性的褐色斑为特征。现代中医临床治疗，多是沿袭历代医家的辨证论治，遣方用药。笔者根据黄褐斑面部发病部位的不同，从中医整体观出发，探讨黄褐斑面部的发病部位与五脏的相关性，创造性采用部位辨证和经络辨证相结合的方法，及注重引经药物的使用，希望为黄褐斑的治疗提供新的思路。

Chloasma is a common pigmentation on facial skin among middle-aged or young women. The characteristic of chloasma is acquired brown spots on exposed facial regions. Modern traditional Chinese medicine (TCM) clinical treatment mostly follows syndrome differentiation and treatment as well as prescriptions of TCM doctors from previous dynasties. On the basis of different facial location of chloasma, the author explored the correlation between the facial lesion location and five zang-organ under the guidance of TCM holism concept. The creativeness of combining division differentiation and channel pattern differentiation, and the application of channel tropism medicine, provide new ideas for chloasma treatment.

国家自然科学基金委青年项目（81302982）：基于“久病入络”理论的当归饮子防治荨麻疹PIP2/IP3/DAG 信号通路的分子研究，负责人：郭静。