目的：开展藏医经典方七十味珍珠丸上市后再评价，提高其科学性、安全性、规范性，促进产业发展。方法：采用文献挖掘法对七十味珍珠丸处方和现代临床药学研究等信息进行整理，借鉴Padma-28 成功实例，分析七十味珍珠丸适应症等存在的不足。结果：梳理了七十味珍珠丸的临床联合用药和药理毒理的研究现状。结论：构建七十味珍珠丸上市后再评价新模式，为藏成药临床合理使用及有效性等提供再评价科学依据。

This study was aimed to carry the post-marketing revaluation on classical Tibetan medicine of the Seventy-flavor Pearl Pill, which will help improve its scientificity, safety and standardization in order to promote its industrial development. Literature mining method was used to summarize research information of the Seventy-flavor Pearl Pill, such as the clinical pharmacy sorting. Meanwhile, the successful example of Padma-28 was referred in the analysis of deficiencies in the indications of Seventy-flavor Pearl Pill. The results showed the present situation of clinical combination therapy, pharmacology and toxicology study of Seventy-flavor Pearl Pill. It was concluded that the building of new model of post-marketing revaluation on the Seventy-flavor Pearl Pill can provide re-evaluation scientific basis for Tibetan medicine on its clinical effectiveness and safety.

教育部中国博士后科学基金项目（2012M511916）：藏医白脉病的潜在生物标志物及七十味珍珠丸的干预研究，负责人：王张；四川省中医药管理局中医药科学技术研究专项（2012-E-040）：藏医白脉病的潜在生物标志物及七十味珍珠丸的干预研究，负责人：王张。