“肾虚膀胱热”是中医脏腑相关理论的重要组成部分，是祖国医学对淋证病因病机的主要概括。现代免疫学认为，粘膜免疫系统由粘膜局部的粘膜相关淋巴组织及免疫细胞共同组成，主要针对经粘膜表面进入的微生物产生应答，抵抗微生物对机体的侵袭。粘膜免疫在尿路感染的发生中发挥着重要作用。本文以“SIgA”和“归巢机制”为基点，探讨粘膜免疫与“肾虚膀胱热”理论相关性，以期更好地挖掘中医“肾虚膀胱热”理论的内涵。

Theory of "Shen-Xu Pang-Guang-Re (SXPGR)" is an important part of the theory of zang-fu in traditional Chinese medicine (TCM). And it is the generalization for etiology and pathogenesis of "Lin-Zheng (LZ)". In immunology, mucosal immune system is composed of mucosal-associated lymphoid tissues and immune cells, which can resist the invasion of microorganisms. Mucosal immune plays an important role in the occurrence of urinary tract infection. This paper, which was based on "SIgA" and "homing mechanism", was to investigate the relevance between mucosal immunity and the theory of SXPGR, in order to study the connotation of SXPGR in TCM.

苏州市科技局“科教兴卫”青年科技项目（KJXW2011027）：PMS 滋肾通关古方对慢性肾盂肾炎大鼠尿SIgA 和T 淋巴细胞亚群表达的影响，负责人：蒋春波。