目的：研究参杞补气颗粒中人参提取最佳工艺条件。方法：采用正交试验对人参提取工艺进行优选，以乙醇浓度、乙醇量、提取时间和提取次数为考察因素，并采用HPLC 法测定浸膏中人参皂苷Rg1、Re、Rb1含量，并以3种皂苷收率为考察指标，确定最佳提取条件。结果：参杞补气颗粒中人参提取最佳工艺为：加入药材6倍量60%乙醇，提取2次，每次3 h。结论：该提取工艺稳定，提取率高，且合理可行。

This study was aimed to optimize the extraction process of ginseng in Shen-Qi Bu-Qi (SQBQ) granules. The orthogonal experiment method was used to optimize the extraction process of ginseng adopting ethanol concentration, ethanol volume, extraction time and extraction times as factors. The content of ginsenoside Rg1, Re, Rb1 content in the extract was determined by HPLC. And the optimum extraction conditions were determined with indexes of three kinds of saponin yield. The results showed that the optimum extraction process of ginseng for SQBZ granules was that adding 6 times amount of 60% ethanol technology for medicinal materials, extract for 2 times, and 3 h for each time. It was concluded that the optimization of ginseng extraction process was stable, reasonable and feasible with high extraction rate.

吉林省科技厅科技发展计划项目（YYZX201284）：参杞补气颗粒保健食品的研究，负责人：吕琳。