围绕假说如何评价和检验这一核心问题，从假说与科学假说的概念入手，借鉴国内外新近研究进展认识，对科学假说的类型、检验方式与验前和验后评价标准进行深入分析，树立起该研究的“科学视野”和“学科标尺”，探查中医学假说认识水平，指出存在问题和差距。藉此，分析论证现代中基“脑调控五脏整体观念”科学假说，证明其属于“科学理论假说”，将会引领中医学假说由传统描述迈向本质阐明的理论变革。

Around the core issue how to evaluate and test hypothesis, starting from the concept of hypothesis and scientific hypothesis, learning form recent progress and understanding at home and abroad, we have analyzed the type of scientific hypothesis, test methods and pre-mortem and post-mortem evaluation criteria in depth, established " scientific vision" and "discipline ruler", explored the awareness level of the Chinese medicine hypothesis, pointed out the problems and gaps. Whereby, we have analyzed and demonstrated "brain regulating five internal organs concept of wholism" scientific hypothesis, and proven it belongs to the "scientific hypothesis". We were confident that these works mentioned above would lead the theoretical reform changing Chinese medicine hypothesis from traditional description to the nature clarification.

国家自然科学基金委员会面上项目（81173151）：雌激素受体β介导的中枢5-HT功能在经前期综合征肝气逆郁两证中的作用，负责人：乔明琦；山东省人民政府“泰山学者”建设工程专项，负责人：乔明琦。