脑卒中后抑郁（PSD）是指脑卒中后引发的抑郁症，属于继发性抑郁症，表现为情绪抑郁、言语减少、睡眠障碍、食欲不佳、兴趣缺乏、精力不足、主动性差、不配合康复治疗等。PSD不仅给患者带来生理上和心理上障碍，还会延缓受损神经功能的恢复，影响生活质量，甚至增加致残率、病死率。因此，为PSD患者研发安全、有效的治疗药物是十分必要的。本文将对西医西药、中医中药及中西医结合治疗PSD的研究进展进行综述。

Post-stroke depression (PSD) referred to the onset of depression after being diagnosed with post-stroke. It was a secondary disease, mainly including depression, little words, sleep disorders, anorexia, absence of interest, undynamic, passiveness, misfitting rehabilitation and so on. It was not only a psychological and physiological disease, but also delay the function recovery of damaged nerves, influence the patient’s quality of life, and increase the rate of disability and mortality. It was essential to research and develop effective and safe treatment medication. This paper reviewed the current situation and developing prospects of western medicine, Chinese medicinal, treatment of integrated traditional Chinese medicine and western medicine in PSD treatment.

河南省卫生厅医学科技攻关项目（201304096）：十全大补汤治疗阿尔茨海默病虚证的临床研究,负责人：李宁宁。