糖尿病认知功能障碍是由糖尿病糖代谢紊乱所导致的代谢、神经化学、形态学、电生理及行为学等方面的改变，表现为推理能力缺失、记忆减退、学习能力下降、注意力不集中、智力减退等症状。本文主要从糖尿病认知障碍的发病机制和中西医治疗等方面研究进展进行系统综述，探索中药多途径、多环节、多靶点的调控作用，扩大临床应用范围，丰富与发展中药配伍理论，发挥中医药辨证论治的优势。

Diabetic cognitive dysfunction,a glucose metabolic disorder,is caused by metabolic, neurochemistrical,morphological,electrical physiological and behavioral changes featuring the disability of reasoning and learning,memory loss,inattention and hypophrenia.In recent years,more attention has been attached to the field of medicine.In this review,a progress of cognitive disorder was systematically explored over the pathogenesis and treatment of both TCM and western medicine,and investigated multi-targets and multiple methods of Chinese herbal researches at multiple stages for expanding the range of clinical application of TCM,enriching and developing the theory of TCM compatibility,and promoting the advantages of TCM syndrome differentiation.

北京市教育委员会科学研究与研究生培养共建项目：中药干预胰岛素抵抗技术平台建设与方药筛选研究，负责人：刘铜华。