目的：通过开展北细辛全球范围内产地生态适宜性分析及品质生态学研究，为北细辛合理规划生产布局提供科学依据。方法：采用中国中医科学院中药研究所自主研发的“药用植物全球产地生态适宜性区划信息系统”（GMPGIS ），以北细辛道地产区、主产区和野生分布区的396个采样点的生态环境因子值为依据，经GMPGIS分析得出北细辛全球范围内的生态适宜产区和潜在种植区。结果：北细辛在世界范围内的生态适宜产区为美国、加拿大、俄罗斯、中国、日本、朝鲜等国家；北细辛在中国的主要适宜产区为黑龙江、吉林、辽宁、陕西、甘肃、湖北、云南等省区。本文同时从品质生态学角度归纳阐述了气候及土壤等因素对北细辛品质的影响。结论：本文研究结果与近年来北细辛主产区及引种区发展相吻合，可为北细辛保护抚育、引种栽培及高品质药材的规范化种植提供科学依据。

The goal of this study was to sift the appropriate producing areas of A.heterotropoides out from the global range using geographic information system for global medicinal plants(GMPGIS),designed by Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences(ICMM).GMPGIS system was in favor of providing scientific basis for rational planning and production layout.In this study,the data of the ecological factors from 396 sample plots of A.heterotropoides was analyzed,including those from both the traditional producing regions as past dynasties medicinal works documented and all the noted production regions in the world.As a result,it was found that the optimum producing areas of A.heterotropoides worldwide mainly distributed in the United States,Canada,Russia,China,Japan,North Korea,etc.Its suitable producing areas in China mainly distributed in Heilongjiang,Jilin,Liaoning,Shaanxi,Gansu,Hubei and Yunnan provinces,etc.In regard to the principles of quality ecology,effects of climite and soil on the quality of A.heterotropoides were summarized.In conclusion,all the outcomes based on GMPGIS chimed with the current reported main producing and introducing areas of A.heterotropoide,providing scientific evidence for preserving,nurturing,introducing and cultivating A.heterotropoides rigorously with fine quality.

科学技术部重大新药创制国家重大科技专项子课题（2014ZX09304307001-014）：中药新药安全性检测技术与标准研究，负责人：李西文；科学技术部重大新药创制专项子课题（2014ZX09301308-007）：苗药芪胶升白胶囊技术改造及再评价研究，负责人：李西文。