2500多年来，“肝令人咳”这一中医理论一直指导着中医医师的临床实践。本文以α1-抗胰蛋白酶缺乏症为切入点，通过从现代医学对α1-抗胰蛋白酶在体内的生成、生理功能、代谢及缺乏所引起的疾病等方面的研究诠释了这一理论的正确性。

For over 2500 years,the traditional Chinese medical(TCM)theory of“liver diseases can lead to cough” has been applied to TCM clinical practice.By the analysis of the production,physiological functions, metabolism and diseases caused by deficiency of α1-antitrypsin,this paper attempts to verify the truth of the theory.

国家中医药管理局全国名老中医药专家传承工作室建设项目：吕明庄全国名老中医传承工作室，负责人：王光义。