[关键词]
[摘要]
中医方证代谢组学(Chinmedomics)是近年来兴起的新兴学科,它整合了系统生物学与中药血清药物化学的理论及技术,形成了鉴定证候生物标记物,建立方剂有效性评价体系,并发现药效物质基础的应用科学。中医方证代谢组学的理论及方法有助于实现建立中国式精准医学模式,有助于进一步提升中医药研发的原始创新能力。
[Key word]
[Abstract]
Chinmedomics is a newly emerging discipline in recent years,integrating the theory and technology of system biology and serum pharmacochemistry of traditional Chinese medicine(TCM).It has formed and established the evaluation system for identifying the syndrome biomarkers and evaluating the effectiveness of prescriptions,and discovering the efficacy substances.The theory and method of chinmedomics is beneficial to establishing a Chinese-style precision medicine,and also helping further enhance the original innovation ability of TCM research and development.
[中图分类号]
[基金项目]
国家自然科学基金委重点项目(81430093):中药体内药效物质基础的系统分析方法学——中医方证代谢组学研究,负责人:王喜军;科学技术部“重大新药创制”国家科技重大专项(2015ZX09101043-011):中药经典名方整合作用机制关键技术研究,负责人:王喜军。