中药的传统功效是在中医理论的指导下，经过长期实践对其临床疗效的高度总结，对中药的临床使用具有重要的指导意义。与现代医药体系相比，中医药体系的诊疗模式与西医不同，且相对于西药，中药作用的疾病靶标可能更加广泛。基于中药的传统功效，结合现代科学技术手段，开展对中药的药效物质基础及其作用机制的研究，有助于疾病治疗中新靶点、新机制和新物质的发现及中药新药的二次研发，对于阐释中药传统功效的现代科学内涵具有深远意义。因此，基于中药传统功效的现代药效物质基础研究是中医药原创性研究的源泉。

The traditional efficacy of traditional Chinese medicine (TCM) is to summarize the clinical efficacy of TCM under the guidance of TCM theory, and it possess important guiding significance for the clinical use of TCM. Comparing with the modern medical system, the TCM system was different from western medicine in diagnosis and treatment modes, and the disease targets of TCM maybe more extensive than that of western medicine. Based on the traditional efficacy of TCM, combined with modern means of science and technology, the research on material basis and pharmacological mechanism of TCM was beneficial to discovery the new targets, new mechanism, new material and the secondary development of new drug of TCM. Furthermore, it also has far-reaching significance on interpret the modern scientific connotation of TCM efficacy. Therefore, deriving from the traditional efficacy of TCM, the research of modern pharmacodynamic material basis is the source for original research.

国家自然科学基金面上项目（81774150）：以生脉制剂为例探讨名方制剂“病-证相关”精准治疗生物学基础的研究方法，负责人：余伯阳。