目的：观察低频负压循经藏腑调理“欲病”的临床疗效。方法：对符合纳入标准随机选取的34例“欲病”受试者，运用低频负压循经藏腑调理的方法进行调理，通过分析“欲病”受试者的罐斑显色反馈性调理信息及调理前、后数字化、量化的中医四诊合参诊断信息，评价其调理效果。结果：经过4周的持续调理，34例“欲病”受试者，与调理前相比，调理后受试者罐斑显色显著变浅甚至消失（P＜0.01）；调理后淡红舌、薄白苔的比例明显升高（P＜0.05），瘀斑舌较调理前减少（P＜0.05）；调理后背痛、颈项强痛、焦虑、易怒的核心症状有不同程度的减轻甚至消失；调理后受试者脉弦紧度显著减小（P＜0.01）。结论：低频负压循经藏腑调理可显著改善“欲病”受试者不适症状，促进“欲病”受试者舌、脉、罐斑病理状态的恢复，该方法值得推广及进一步探索。

This study was aimed to observe the clinical effect of low frequency negative pressure meridian visceraregulating sub-health. According to the diagnostic criteria, 34 cases of sub healthy subjects were randomly selected. Thelow frequency negative pressure meridian viscera regulating method was used. By analyzing the cupping spot colorfeedback conditioning information of the sub healthy subjects and conditioning before and after the synthesis of the fourdiagnostic methods of digital and quantitative, its effect was evaluated. After 4 weeks of continuous adjustment, 34 casesof sub healthy subjects, compared with preconditioning, cupping spot color of the subjects was shallow or disappeared(P < 0.01); after adjusting, the proportion of light red tongue and thin white tongue coating increased obviously (P < 0.05),the proportion of ecchymosis tongue was decreased compared to precoditioning (P < 0.05); after adjustment, coresymptoms such as back pain, neck pain, anxiety and irritability, were alleviated or disappeared; after adjustment, thepulse string tightness decreased significantly (P < 0.01). It was concluded that the low frequency negative pressuremeridian viscera regulation can significantly improve discomfort symptoms of sub healthy subjects and promote therecovery of tongue, pulse and cupping spot color in sub healthy subjects. This method is worth popularizing and furtherexploring.

科技部对发展中国家科技援助项目（KYZ201302010）：中墨联合针灸介入临终关怀的策略及临床研究，负责人：牛欣；国家自然科学基金面上 项目（81473553）：基于人体生物学信息动态检测的气血津液网络构建及其辨识机制，负责人：牛婷立；国家自然科学基金面上项目 （81573880）：基于人体气味、声音的中医闻诊气机生物学网络构建及机制探讨，负责人：牛欣。