目的：分析临床实践中神经根型颈椎病（cervical radiculopathy，CR）中成药应用规律。方法：从 2012年12月至2014年7月利用中医医疗与临床科研信息共享系统采集CR临床数据，研究对象为中国中医科 学院望京医院就诊的628例CR住院与门诊患者。以使用中成药人群为研究对象，应用复杂网络liquorice软件 计算中成药与西药、中成药与外用中药制剂应用的关联频度和互信息值，并绘制复杂网络图。结果：中成药使 用例数分析，排在前两位的中成药为瘀血痹胶囊、颈舒颗粒。中成药与西药联合应用频次分析，颈舒颗粒与注 射用腺苷钴胺联用频次最高，关联频度为822，互信息值为268.07。中成药与外用药物联合应用频次分析，痹祺 胶囊与代温灸膏临床联用频次最高，关联频度为384，互信息值为1754.76。结论：进一步证实中成药治疗CR患 者是以活血化瘀、通络止痛为基本治法。中西药联用、中药制剂内服外用联合在实践中应用广泛，联合用药的 疗效、作用特点及安全性有待验证。

Objective: Analyze the clinical application rule of Chinese patent medicine in cervical radiculopathy (CR). Method: The clinical real-world data of CR were extracted by using information sharing system of traditional Chinese medicine and clinical research. Six hundred and twenty-eight inpatients and out patients with CR were enrolled from December 2012 to July 2014 in the information system database of Wangjing Hospital. The correlation analyses and mutual information value were recorded for Chinese patent medicine therapy application of all patients by using liquorice software. Complex network diagrams were generated. Result: Yuxuebi capsule and Jingshu granule is the highest frequency in application of Chinese patent medicine. Jingshu granule and Cobamamide for injection were the highest frequency in combined application of Chinese patent medicine and western medicine. Association frequency was 822, mutual information value was 268.07. Biqi capsule and Daiwenjiu cream were the highest frequency in combined application of Chinese patent medicine and topical drugs. Association frequency was 384, mutual information value was 1754.76. Conclusion: The basic treating principle for CR was promoting blood circulation and removing blood stasis. The efficacy and safety of combined Chinese patent medicine with other medicine need further research

国家中医药管理局中医药行业科研专项（201207001-04）：全国中医医疗与临床科研信息共享的推广应用研究，负责人：高云；国家中医药管理 局国家“十二五”科技支撑计划课题（2013BAI02B10）：“病证结合”中医药真实世界临床科研方法学研究，负责人：谢琪；国家科技部中国中医 科学院科技创新优势团队资助项目（YS1304）：骨与关节退行性病变中医防治，负责人：朱立国。