目的：构建适合女性中医健康管理需求的干预知识库，探索干预知识库长期发展的机制。方法：根据女性中医健康状态特点，设计女性中医健康干预知识库的架构，研究基于辨证施食理论的食疗方案与女性健康状态关联的推理机，设计基于大数据和疗效反馈机制的中医健康干预知识库长期发展机制。结果：女性中医健康干预知识库分类属性包括已病状态下的病证分类以及未病和欲病状态下的脏腑功能、气血阴阳和病邪状态，食疗方推理机根据食材地域、季节、四气、补益、祛邪等特性匹配女性健康状态，根据干预效果反馈不断修正和完善干预方案的适宜对象特征。结论：研究提出的女性中医健康干预知识库构建方案能满足女性中医健康管理干预的需求，根据疗效反馈不断修正干预方案的方法有利于干预知识库逐步实现精准推荐和长期发展。

Objective: To fulfill the TCM (traditional Chinese medicine) health management needs of female through constructing the intervention knowledge base, explore the long-term development mechanism of intervention knowledgebase. Methods: The structure of female TCM Health Intervention Knowledge was designed base according to the characteristics of TCM health status of females. The inferential mechanism by studying the relation between the female health status and the diet therapy scheme was explored based on syndrome differentiation. A Long-term development mechanism of TCM health intervention knowledge database was designed based on big data and effect feed back mechanism. Results: The classification standard of the TCM Health Intervention Knowledge base of female includes the state of the viscera functions, qi and blood, yin and yang, and pathogenic properties of the body under the illness and health condition. The dietary therapy formula inference engine can provide food material according to the region, natures, function of tonifying, evil eliminating, to match the female health status, and constantly adjusting and improving the Intervention plan according to the feedback. Conclusion: The study proves the construction plan of TCM Health Intervention Knowledge base of female is able to meet the needs of female TCM health management intervention, and the method of constantly adjusting and improving the intervention plan according to the feedback helps to realize the precisere commendation and long-term development of intervention knowledge base.

江西省科技厅重点研发计划项目（20171ACG70011）：基于智慧诊疗云平台的江西省名老中医资源挖掘整理研究，负责人：查青林；香港浸会大学与深圳君兰电子科技有限公司合作项目：脉诊与中医移动健康，负责人：吕爱平