目的：通过文献检索、共现分析和聚类分析等文献计量学分析，探讨中医药干预干细胞治疗缺血性心脏病的研究现状与热点,方便为该领域今后的相关研究提供参考。方法：检索中国知网和PubMed数据库中收录的中医药干预干细胞治疗缺血性心脏病相关的文献，运用书目共现分析系统软件（BICOMB）、CytoScape3.6.1及SPSS软件对高频词进行共现分析和聚类分析。结果：从中国知网检索到文献116篇，频次≥3的高频词共43个，共有226对共现关系，聚类共分别出7个类别；从PubMed检索到文献44篇，频次≥3的高频词共35个，共有355对共现关系，聚类共分别出8个类别。结论：中医药干预干细胞治疗缺血性心脏病的研究在2005年之后在世界多个国家开始兴起，中药、益气温阳活血方、三七总皂苷、地黄低聚糖、丹参注射液、丹参6个方面是在中医药范围内的研究热点。

Objective: To explore the research focus on Chinese medicine intervene stem cells in the treatment of ischemic heart disease and provide reference for the future research in this field by retrieving, co-occurrence analyzing and clusteranalyzing of quantitative analysis the related literature. Methods: The literatures related to this study were retrieved fromthe China Knowledge Resource Integrated Database (CNKI) and PubMed database. The high frequency words were cooccurrenceanalyzing and cluster analyzing by bibliographic item co- occurrence matrix builder (BICOMB) software,Cytoscape3.6.1 drawing software and SPSS statistical analysis software. Results: In CNKI, there were 116 literaturespublished and 43 high frequency words (frequency > 3 times), and it had 226 co- occurrence relation among highfrequency words. The high- frequency words were clustered into 7 categories. In PubMed, there were 44 literaturepublished and 35 high frequency words (frequency >3 times), and it had 355 co- occurrence relation among highfrequency words. The high- frequency words are clustered into 8 categories. Conclusion: The research of Chinesemedicine intervene stem cells in the treatment of ischemic heart disease was more and more popular in the world after2005. The hot researches on traditional Chinese medicine are 6 aspects of Chinese herbal medicine, Yiqi WengyangHuoxue Formula, Panax notoginseng, Rehmannia glutinosa oligosaccharides, Danshen injection and Radix SalviaeMiltiorrhizae.

广西科学技术厅应用开发研究项目（桂科攻1598012-55）：中医药干预干细胞治疗缺血性心肌病转化医学平台建设与应用，负责人：郑景辉；国家自然科学基金委基础研究项目（81660776）：基于线粒体脂质-蛋白质组学的养心通脉有效部位方抗大鼠心肌缺血再灌注损伤机制的研究，负责人：郑景辉。