目的 探讨赵宗江教授运用益肾解毒化瘀方治疗慢性肾脏病（Chronic Kidney Disease CKD）32例 患者的经验和临床疗效。方法 收集CKD肺肾气虚，瘀毒内阻型患者共32例，疗程为6个月和1年，对其治疗 前后的中医症状积分及疗效指标的变化进行对比分析，评估其肾功能及临床症状改善情况。结果 32例患 者经中医疗效评定，6个月疗程后显效者8例，有效者23例，无效者1例；1年疗程后临床痊愈者11例，显效者 18例，有效者3例。综合疗效评定6个月疗程后临床控制者4例，显效者24例，有效者4例；1年疗程后临床 控制者 17 例，显效者 15 例。且益肾解毒化瘀方对 24 h 尿蛋白定量、血肌酐及血尿酸的升高均有改善作用 （P < 0.05）。结论 益肾解毒化瘀方治疗CKD中医辨证属肺肾气虚，瘀毒内阻者，可明显降低患者的蛋白尿、 血肌酐和血尿酸水平，维持并改善肾功能，缓解临床症状，提高生活质量。

Objective To explore the experience and clinical efficacy of Zhao Zongjiang ??s lecture on the use of Yishen Jiedu Huayu Decoction for 32 patients with chronic kidney disease (CKD). Methods We collected 32 cases with CKD of lung kidney qi deficiency syndrome and internal stagnation of stasis and toxin syndrome. The course of treatment was 6 months and 1 year. We contrasted and analyzed TCM symptom scores and changes in western medical efficacy indicators before and after the treatment to assess the improvement of renal function and clinical symptoms. Results 32 cases were evaluated by the Chinese medical efficacy assessment. 8 cases were markedly effective, 23 cases were effective, and 1 case was ineffective after 6 months; 11 cases were recovered, 18 cases were markedly effective, 3 cases were effective after 1 year; Evaluated by the comprehensive efficacy assessment, 4 cases were clinically controlled, 24 cases were markedly effective, and 4 cases were effective after 6 months; 17 cases were clinically controlled, 15 cases were markedly effective after 1 year; Yishen Jiedu Huayu Decoction can also reduce the 24-hour UTP, creatinine and serum uric acid levels (P < 0.05). Conclusion Yishen Jiedu Huayu Decoction for the treatment of CKD can significantly reduce proteinuria and improve renal function and improve the quality of life.

北京市朝阳区卫健委中医人才培养项目