随着膳食结构和生活方式的改变,肥胖的发病率显著升高。近年来，越来越多的研究表明，肠道菌群在肥胖及其代谢性疾病的发生过程中发挥重要作用。本文将阐述肠道菌群改变与肥胖发生的关系,肠道菌群紊乱引起肥胖的作用机制，并总结中医药通过影响肠道菌群干预肥胖的研究进展。

With the changes in dietary structure and lifestyle, the incidence of obesity has increased significantly. In recent years, increasing evidence shows that gut microbiota plays an important role in the development of obesity and related metabolic disorders. This article summarizes the relationship between gut microbiota and obesity, the underlying mechanisms for gut microbiota changes on obesity and related metabolic disorders. Furthermore, we review the progress of Chinese medicine in treating obesity by regulating gut microbiota.

江苏省中医药局科技项目（FY201706）：基于肠道菌群调节探讨中药小陷胸汤改善超重、肥胖2型糖尿病代谢紊乱作用机制，负责人：谢绍锋。国家科技支撑计划（2015BAI12B14）：中国成人糖尿病的发病危险因素、动态监测及综合防治，负责人：刘超。