目的 通过探索地黄相关专利保护的技术布局、主题分布等方面的规律与特征，为地黄药物研发和生产机构的管理运营及知识产权保护提供参考与建议。方法 以国内外专利为数据源，利用智慧芽专利分析平台和EXCEL软件对近20年来地黄相关药物的专利年度申请态势、技术布局、主要申请机构及其运营情况进行统计与分析。结果 地黄相关专利从2010开始快速增长，但授权发明少；在地黄的种植栽培方面，专利的申请量较少，有待加大该领域专利布局力度。在地黄的加工炮制和药物新用途方面，原始创新有着较大空间。结论 建议地黄研发机构应围绕核心产品对其专利进行全面布局，分析专利价值并进行分类管理和运营，关注该领域专利申请动态预警和防范侵权和被侵权，同时应注重“知识产权”先行，开拓国际市场。

Method In this paper, using the international patents about Radix Rehmanniae as data source, the trend of patent application situation, techniques distribution, application institutions and their operations were statistical analyzed by PATSNAP and EXCEL in recent twenty years.Result Based on the analysis method proposed here, we concluded that the patent quantity about Radix Rehmanniae is increased rapidly from 2010. In the cultivation and cultivation of Rehmannia glutinosa, the number of patent applications is small, and it is necessary to increase the layout of patents in this field. In the processing and processing of rehmannia and the new use of drugs, there is much room for original innovation.Conclusion It is suggested that the R&D institutions should apply for patents strategically fully around the core products, analyze the patent value, manage patent by classification, conduct patent early warning to prevent infringement and infringement and focus on exploring the international market.