目的 探讨慢性萎缩性胃炎患者的舌象特点，分析胃粘膜病理学改变与中医舌象变化的相关性。方法 本研究运用舌象仪采集慢性萎缩性胃炎患者的舌象信息，采用病例对照研究方法比较不同病理阶段的胃病患者舌象客观参数和特征，描述舌象特征的变化趋势，分析慢性萎缩性胃炎患者较常见的舌象特征。结果 慢性萎缩性胃炎组的舌色参数R值和V值显著高于慢性非萎缩性胃炎组与胃癌组（P < 0.05）；慢性萎缩性胃炎组中舌质红的患者显著多于慢性非萎缩性胃炎组与胃癌组（P < 0.01）；慢性萎缩性胃炎组的舌苔厚薄指数和剥苔指数均显著低于慢性非萎缩性胃炎组与胃癌组（P < 0.01），慢性萎缩性胃炎组中舌苔厚的患者显著多于慢性非萎缩性胃炎组与胃癌组（P < 0.01）；结论 舌质红和舌苔厚是慢性萎缩性胃炎患者常见的舌象特征。

Objective To investigate the characteristics of tongue image in patients with Chronic atrophic gastritis (CAG) and analyze the correlation between the pathological changes of gastric mucosa and the changes of tongue manifestation in traditional Chinese medicine.Methods Tongue image analysis instrument was used to collect the tongue imaging information of patients with CAG. The case-control study was used to compare the objective parameters and characteristics of tongue imaging in patients with gastric diseases at different pathological stages, describe the change trend of tongue imaging characteristics, and analyze the common tongue imaging characteristics of patients with CAG.Results The R and V values of tongue color parameters in CAG group were significantly higher than those in chronic non-atrophic gastritis group and gastric cancer group (P < 0.05). The patients with tongue red color in CAG group were significantly more than those in chronic non-atrophic gastritis group and gastric cancer group (P < 0.01). The tongue coating thickness index and coating peeling index of CAG group were significantly lower than those of chronic non-atrophic gastritis group and gastric cancer group (P < 0.01), and the patients with thick tongue coating in CAG group were significantly higher than those of chronic non-atrophic gastritis group and gastric cancer group (P < 0.01).Conclusion Red tongue and thick tongue coating are common features of CAG.

国家自然科学基金项目面上项目（81873236）：基于复杂生物网络技术的慢性萎缩性胃炎湿热证诊断模型构建；负责人：刘国萍。国家中医药管理局第四批全国中医（临床、基础）优秀人才项目，负责人:刘国萍。上海市健康辨识与评估重点实验室（No. 13DZ2261000）,负责人：王忆勤。