目的 评估联合应用极速成像技术与脉象仪检测冠心病患者动脉弹性的价值。方法 联合应用超声极速成像技术与脉象仪对44例冠心病患者及40例健康人（对照组）分别行颈动脉脉搏波传导速度（PWV，pulse wave velocity）及桡动脉脉象参数的检测。检测颈动脉脉搏波传导速度使用的是法国Supersonic Aixplorer彩超仪所配备的极速成像技术，包括两个参数：即收缩期起始时的PWV-BS（BS，beginning of the systole）及收缩期结束时的PWV-ES（ES，ending of the systole）；检测桡动脉脉象参数使用的是DDMX--100脉象仪，包括诸多参数，如h1、h3/h1、h4/h1、h5/h1、h3、h4、h5、t、w1、w1/t、w2、w2/t等；冠心病组及对照组数据采用SPSS 18.0统计软件进行组间数据分析对比，同一观察对象的两种技术参数的相关性分析采用Spearman非参数法进行。结果 冠心病组的PWV-BS、PWV-ES均高于对照组（P < 0.05）。冠心病组h3、h4、h3/h1、h4/h1均高于对照组（P < 0.05）。冠心病组PWV-BS、PWV-ES与h3、h3/h1、h4/h1呈正相关（P < 0.05），对照组PWV-BS、PWV-ES与h3/h1、h4/h1呈正相关（P < 0.05）。结论 联合应用极速成像技术与脉象仪能够客观评估冠心病患者的动脉弹性功能，为临床综合评估冠心病患者动脉弹性提供新方法。冠心病患者诸多脉象参数与极速成像技术参数PWV-BS、PWV-ES间呈现出了很好的相关性，进而拓展和完善了脉象客观化领域的研究。

Objective To evaluate the value of UltraFast imaging combined with pulsography in the detection of arterial elasticity in patients with coronary artery heart disease (CHD) and to analyze the correlation between the two techniques. Methods The pulse wave velocity (PWV) of carotid artery and the pulse parameters of radial artery were detected in 44 patients with CHD and 40 healthy volunteers (control group). The PWV of carotid artery was detected by French Supersonic Aixplorer which built-in UltraFast imaging, including the PWV of the beginning of the systole (BS) and the ending of the systole (ES). The pulse parameters of radial artery were detected by DDMX-100 pulsography, including h1, h3/h1, h4/h1, h5/h1, h3, h4, h4, h5, t, w1, w1/t, w2, w2/t, etc. The data of CHD group and control group were analyzed and compared by SPSS 18.0 statistical software. The correlations between the parameters of the two techniques were analyzed by Spearman non parametric method. Results The PWV of the CHD group at the BS and ES were higher than those of the control group (P＜0.05). The pulse parameters such as h3、h4、h3/h1 and h4/h1 of the CHD group were higher than those of the control group (P＜0.05). There were positive correlations between the PWV-BS, PWV-ES and the pulse parameters such as h3, h3/h1, h4/h1 in the CHD group (P＜0.05) and also between the PWV-BS, PWV-ES and h3/h1, h4/h1 in the control group. Conclusion UltraFast imaging technique combined with pulsography can assess the artery elasticity in patients with CHD and provides a new method for clinical evaluation of arterial elasticity in these patients. The PWV-BS, PWV-ES and the pulse parameters in patients with CHD revealed a significant correlation of the two techniques, which further expands and improves the research of pulse objectification.

上海市卫生计生委人才类项目（沪卫计中发【2018】23号）(ZY（2018-2020）-RCPY-2003)：上海市进一步加快中医药事业发展三年行动计划（2018-2020）高级中西医结合人才计划，负责人：高东雯；上海中医药大学预算内科研项目（2015YSN35）：基于超声极速成像技术评价原发性高血压患者动脉弹性的可行性研究，负责人：高东雯。