[关键词]
[摘要]
目的 采用数据挖掘方法探析朱丹溪治疗痛风的用药规律。方法 借助中医传承辅助平台软件(V2.5)及古今医案云平台软件(V1.6.3),对《格致余论》《金匮钩玄》和《丹溪心法》三部著作中治疗痛风用药规律进行分析。结果 纳入32首治疗痛风的方药,包括中药90味,其中使用频次较高的为甘草、苍术、川芎、黄柏、当归、生姜和黄芩;用药以温性和平性,归脾、肝、心和肺经中药为主;功效以活血化瘀、发散风寒、清热燥湿、补气和补血为主;演化得到8个核心组合及4个新方。结论 朱丹溪治疗痛风着眼于其病因病机“热血得寒,汙浊凝涩”,药物的选用以治血为本,多用辛温苦燥之品,活血行瘀的同时散燥寒湿。
[Key word]
[Abstract]
Objective To analyze the medication regularity of Zhu Danxi''s treatment of gout by using data mining.Methods With the help of Assistant Platform of Traditional Chinese Medicine Inheritance (V2.5) and the Ancient and Modern Consilia Cloud Platform (V1.6.3), the rules of medication for gout in Ge Zhi Yu Lun, Jin Gui Gou Xuan and Dan Xi Xin Fa were analyzed.Results A total of 32 prescriptions for gout were included, involving 90 medicinals of traditional Chinese medicines (TCM). The top 7 used were Radix Glycyrrhizae, Rhizoma Atractylodis, Rhizoma Ligustici Chuanxiong, Cortex Phellodendri, Radix Angelicae Sinensis, Rhizoma Zingiberis Recens, and Radix Scutellariae. The nature of those medicinals were mainly warm and neutral, and entered the channels of spleen, liver, heart and lungs. The medicinals were mainly used to invigorate blood and dissolve stasis, disperse wind-cold, clear heat and dry dampness, supplement qi and blood. A total of 8 core combinations and 4 new prescriptions were found.Conclusion Zhu Danxi''s treatment of gout focuses on its pathogenesis: “blood suffering from cold leading to fouling and congealing”, and the medicinals are chose to treat blood. Acrid-warm and bitter-dry medicinals were usually used to active blood circulation and disperse cold and dampness.
[中图分类号]
R259
[基金项目]