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[摘要]
近年来随着胃癌前病变(precancerous lesions of gastric carcinoma, PLGC)的发病率不断上升,基础研究也就成为了重中之重,正确的动物模型选择为临床研究提供了基础,针对不同的需求选择合适的模型。查阅国内外文献发现胃癌前病变的模型多种多样,有免疫模型、Hp感染模型、化学制剂诱导模型等,为寻求更为理想的动物模型,现将近年来关于胃癌前病变的造模方法进行总结,并且归纳和分析。
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[Abstract]
In recent years, with the increasing incidence of precancerous lesions of gastric carcinoma, clinical basic research has become a top priority. Correct selection of animal models provides a basis for clinical research, and appropriate models are selected according to different needs. A variety of models of chronic atrophic gastritis have been found in domestic and foreign literatures, including immune models, Hp infection models, and chemical induction models, etc. In order to find a more ideal animal model, the modeling methods of precancerous lesions of gastric carcinoma in recent years were summarized and analyzed.
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