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[摘要]
目的 搜集《中华医典》[1]中《普济方》[2]治疗痞满的方剂,跨学科运用古今医案云平台(V2.3.5)大数据库,总结中药治疗痞满的临床应用规律。方法 选取《普济方》中治疗痞满的处方,建立标准化医案数据库,采用古今医案云平台(V2.3.5)统计用药频次、药物属性(药性、药味、归经),并进行聚类分析,建立Excel数据库,并批量导入,从单味药频次、性味、归经、功效、药对关联和聚类处方以及复杂网络分析等角度进行分析。结果 筛选后共纳入429首方剂,包含种256种中药,总用药频次3772次;功效371个,总功效频次10712次;四气9种,总频次3580次;五味11种,经计算总频次5888次;12经总频次10210次。治疗痞满应用频次较高的药物前3位为陈皮、白术、人参;关联性药对以人参-白术出现最高,常用药物可聚为4类。结论 运用古今医案云平台(V1.4.5)分析数据,以图表展示出《中华医典》中治疗痞满的用药规律,分析临床治疗痞满的病机,为临床实践中药治疗痞满总结提供参考。
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[Abstract]
Objective To collect the prescriptions for the treatment of distention and fullness from Puji Prescription in Chinese Medical Dictionary, and to summarize the clinical application law of traditional Chinese medicine in the treatment of distention and fullness by using the cloud platform (V2.3.5) database of ancient and modern medical records.Methods The prescriptions for treating distention and fullness in Puji Prescription were selected, and a standardized medical record database was established. The ancient and modern medical record cloud platform (V2.3.5) was used to count the frequency of herb use, herb properties (properties, taste, and channel tropism), and cluster analysis was performed. An Excel database was established, and imported it in batches. The data was analyzed from the perspectives of single herb frequency, nature and flavor, meridian tropism, efficacy, herb pair association and clustering prescription, and complex network analysis.Results After screening, a total of 429 prescriptions were included, including 256 kinds of traditional Chinese medicines, with a total frequency of 3772; 371 actions with a total frequency of 10712; 9 types of four qi with a total frequency of 3580; 11 kinds of five flavors, with a total frequency of 5888; 12 meridians with a total frequency of 10210. The top 3 herbs with higher frequency of application for the treatment of distention and fullness were Pericarpium Citri Reticulatae, Rhizoma Atractylodis Macrocephalae, and Radix Ginseng; the related herb pair was Radix Ginseng - Rhizoma Atractylodis Macrocephalae, and the commonly used herbs can be grouped into 4 categories.Conclusion The ancient and modern medical records cloud platform (V1.4.5) was to analyze the data, showing the medication rule in the Chinese Medical Dictionary for the treatment of distention and fullness. The pathogenesis of the clinical treatment of distention and fullness is analyzed to provide a reference for the summary of the clinical practice of traditional Chinese medicine for the treatment of distention and fullness.
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