高血压作为心脑血管疾病发生和死亡最主要的独立危险因素，严重危害人类健康。近年来，越来越多的学者关注针刺对高血压的治疗作用。本文基于“脉胀”理论，从理论、临床和机制三方面对针刺阳明经穴治疗高血压的研究现状进行系统综述。整理发现“脉胀”理论为针刺阳明经穴治疗高血压奠定了中医理论基础，针刺阳明经穴具有良好的降压效应，其机制可能与纠正血管重构，调节肾素-血管紧张素-醛固酮系统，改善内皮功能，抑制免疫炎症，调节肠道菌群和血管保护作用有关。本文基于“脉胀”理论，梳理从阳明论治高血压的相关研究，为后续进一步研究针刺治疗高血压提供参考，为探讨针刺治疗高血压的选穴方案提供思路。

Hypertension, as the most important independent risk factor of cardiovascular and cerebrovascular diseases, seriously endangers human health. In recent years, more and more researchers pay attention to the therapeutic effect of acupuncture for hypertension. From the prospect of "Maizhang" theory, we systematically reviewed the research status of acupuncture at Yangming meridian in the treatment of hypertension from three aspects: theoretical researches, clinical trials and mechanism researches. We found that the "Maizhang" theory was the theoretical foundation of acupuncture treatment for hypertension from Yangming meridian, which has a good hypotensive effect. Its mechanism may be related to the correction of vascular remodeling, the regulation of renin-angiotensin-aldosterone system, the improvement of endothelial function,the regulation of intestinal flora and the vascular protection. Based on "Maizhang" theory, we summarized the researches on acupuncture for hypertension from Yangming meridian, so as to provide reference for further study of acupuncture on hypertension, and provide direction for the acupuncture protocol on hypertension.

国家自然科学基金委员会青年科学基金课题（81704137）：基于Ghrelin介导的PI3K/Akt/eNOS信号通路研究高血压从阳明论治的分子机制；负责人：李涓；国家自然科学基金委员会面上项目（82074516）：基于RVLM区RAS双轴及其下游通路介导的神经炎症与交感神经兴奋探讨从阳明论治高血压的中枢机制；负责人：李涓；四川省科技厅应用基础研究项目（2019YJ0331）：基于肠道菌群调控Ghrelin介导的p38MAPK信号转导通路探讨高血压从阳明论治的机制研究；负责人：李涓。