目的 了解稳定性冠心病痰瘀互结证所占比例及其相关影响因素，为制定防治策略及方法提供基础资料和依据。方法 基于全国23省市的稳定性冠心病被调查者的中医证候流行病学调查数据，了解痰瘀互结证的占比及其与饮食、吸烟、饮酒、身体活动、情绪状态的关系。采用SPSS 20.0软件进行χ²检验、t检验、多因素Logistic回归分析。结果 共纳入被调查者3172名，其中诊断为痰瘀互结证者1623名，非痰瘀互结证者1549名，痰瘀互结证占比为51.17%。饮食方面，偏嗜咸（OR=1.245， 95% CI=1.041-1.490）、偏嗜辛辣（OR=1.713， 95% CI=1.366-2.147）、偏嗜热食（OR=1.415， 95% CI=1.017-1.969）、偏嗜油腻（OR=1.824， 95% CI=1.455-2.286）是痰瘀互结证发生的危险因素（P < 0.05）；饮酒（OR=0.787， 95% CI=0.622-0.996）是痰瘀互结证的保护因素（P < 0.05）。情绪方面，轻度抑郁（OR=2.209， 95% CI=1.832-2.665）、中度抑郁（OR=3.133， 95% CI=2.070-4.742），轻度焦虑（OR=1.337， 95% CI=1.048-1.705）、中度焦虑（OR=2.113， 95% CI=1.162-3.844）是痰瘀互结证发生的危险因素（P < 0.05）。结论 健康的膳食口味习惯、良好的情绪管理以及适量饮酒可能是防治冠心病痰瘀互结证的有效方法。

Objective To explore the constitution and related influencing factors of stable coronary heart disease (CHD) with phlegm and blood stasis syndrome in order to provide reference for prevention and treatment strategies.Methods The stable CHD patients in 23 provinces and cities of China from 2017 to 2018 were selected to analyze the constitution of phlegm and blood stasis syndrome and its relationship with diet, smoking, drinking, physical activity and emotional state. SPSS 20.0 software was used for χ² test, t test and multivariate logistic regression analysis.Results 3172 patients were included, of which 1623 were diagnosed as phlegm and blood stasis syndrome and 1549 were non-phlegm and non-blood stasis syndrome, Phlegm and blood stasis syndrome accounts for 51.17%. In terms of diet, salty food (OR=1.245, 95% CI=1.041-1.490), spicy food (OR=1.713, 95% CI=1.366-2.147), hot food (OR=1.415, 95% CI=1.017-1.969) and greasy food (OR=1.824, 95% CI=1.455-2.286) were the risk factors of phlegm and blood stasis syndrome (P < 0.05). Drinking (OR=0.787, 95% CI=0.622-0.996) was the protective factor of phlegm and blood stasis syndrome (P < 0.05). In terms of emotion, mild depression (OR=2.209, 95% CI=1.832-2.665), moderate depression (OR=3.133, 95% CI=2.070-4.742), mild anxiety (or=1.337, 95% CI=1.048-1.705) and moderate anxiety (OR=2.113, 95% CI=1.162-3.844) were risk factors of phlegm and blood stasis syndrome (P < 0.05).Conclusions Healthy eating habits, good emotional management and moderate drinking may be effective methods for phlegm and blood stasis syndrome of CHD.

国家科学技术部国家重点研发计划中医药现代化研究专项（2019YFC1708501）：冠心病等疾病痰瘀互结病因病机与诊治方案创新研究，负责人：胡镜清；佛山市科技创新项目中医药领域先行先试科技攻关专项（2020001005585）：痰瘀互结相关慢病社区防控体系网格化示范应用研究”，负责人：胡镜清；国家科学技术部国家重点基础研究发展计划（973计划）（2014CB542903）：中医证候临床辨证的基础研究，负责人：胡镜清。