目的 探究全国名中医王檀教授应用助阳补肺除痹汤联合肺康复对特发性肺纤维化患者的临床疗效。 方法 回顾性分析2024年1月至2024年11月于长春中医药大学附属医院肺病科住院部和王檀教授长江学者工作室门诊就诊，且满足纳入条件的肺痹患者总数79例。对照组30例，治疗组49例。其中对照组接受常规治疗同时给予助阳补肺除痹汤，治疗组在此基础上加肺康复治疗（步行、哑铃、攀爬楼梯、弹力带、呼吸训练器、沙袋、腹式呼吸锻炼），疗程1个月。对比治疗前后两组患者的肺功能恢复情况、６分钟步行距离、超敏C反应蛋白（CRP）、生活指令评估、治疗总疗效等指标。 结果 在治疗后，分析两组患者肺功能指标、运动耐力、治疗总疗效、炎症反应及生活质量评估治疗组患者疗效优于对照组（P＜0.05），且随访3个月的肺功能治疗组远期效果较好。 结论 助阳补肺除痹汤联合肺康复治疗特发性肺纤维化患者有助于患者各项指标改善，对患者的肺功能改善、运动耐力、生活质量的提高都有益处。

Objective To investigate the clinical efficacy of National Famous Traditional Chinese Medicine Doctor Prof. Wang Tan's application of Yang-assisting Lung Repairing and Paralysis Removing Soup combined with Pulmonary Rehabilitation on patients with idiopathic pulmonary fibrosis. Method A total of 79 patients with pulmonary arthralgia who met the inclusion criteria and visited the inpatient Department of Pulmonary Disease in the Affiliated Hospital of Changchun University of Traditional Chinese Medicine and Professor Wang Tan's Changjiang Scholar Studio from January 2024 to November 2024 were retrospectively analyzed. There were 30 cases in control group and 49 cases in treatment group. Among them, the control group received routine treatment and was given Zhuyang Bufei Chubi decoction, and the observation group was added lung rehabilitation treatment on this basis, the course of treatment was 1 month. Lung function recovery, 6-minute walking distance and therapeutic effect were compared between the two groups before and after treatment. Result After treatment, the pulmonary function index, exercise endurance, total therapeutic effect, inflammatory response and quality of life of the two groups were analyzed, and the curative effect of the treatment group was better than that of the control group (P < 0.05). Conclusion The treatment of idiopathic pulmonary fibrosis patients with Yang-assisted Lung Tonic and Paralysis Removal Soup combined with pulmonary rehabilitation helps patients with various indexes to improve their lung function, exercise endurance, and quality of life.

国家重点研发计划中医药现代化研究专项