慢传输型便秘（STC）是一种临床常见的功能性胃肠道疾病，其发病机制尚未完全明确，目前的诊疗规范亦存在一定局限性。近年来，“脑-肠轴”理论揭示了大脑与肠道之间复杂的双向调节机制，为STC的研究和诊疗提供了新的视角。中医理论认为肠脑之间联系密切，且在辨治STC方面积累了丰富的经验，形成了独特的诊疗思路。本文以《伤寒论》阳明病篇“夫实则谵语，虚则郑声”与“脑-肠轴”理论为基础，阐述“脑-肠轴”与STC之间的关系，同时将“夫实则谵语，虚则郑声”与“脑-肠轴”理论相结合，分析阳明经虚实对神志的影响以及“脑-肠轴”调节的机制，并根据不同证候提出相应治法。通过将《伤寒论》中相关条文与现代医学的“脑-肠轴”理论相融合，本文对 STC 的辨治规律进行了初步探析，以期为推动更全面地认识STC的发病机制及开发更有效的治疗策略提供理论依据。

STC is a kind of clinically common functional gastrointestinal disease. Its pathogenesis hasn"t been completely clarified, and current diagnosis and treatment norms are certainly limited. In recent years, "Brain-Gut Axis theory has unveiled the complex bidirectional regulation mechanism between brain and intestinal tract, rendering new perspective for the research and treatment of STC. TCM theory demonstrates that there is close connection between brain and gut, has formed abundant experience in discrimination and treatment of STC and formed unique diagnosis and treatment ideas. Based on the theory of "excess syndrome is corresponding to Zhanyu, deficiency syndrome is corresponding to Zhengsheng in the chapter on Yangming diseases in "Treatise on Febrile Diseases this paper elaborates on the relationship between the "Brain-Gut Axis and STC. Meanwhile, by combining the theory of " excess syndrome is corresponding to Zhanyu, deficiency syndrome is corresponding to Zhengsheng " with the "Brain-Gut Axis theory, it analyzes the influence of the excess and deficiency of the Yangming meridian on the mental state as well as the regulatory mechanism of the "Brain-Gut Axis and puts forward corresponding treatment methods according to different syndromes. By integrating the relevant provisions in "Treatise on Febrile Diseases with the "Brain-Gut Axis theory of modern medicine, this paper makes a preliminary exploration of the laws of differentiating and treating STC, aiming to provide a theoretical basis for promoting a more comprehensive understanding of the pathogenesis of STC and developing more effective treatment strategies.

国家中医药管理局2019年度中医药专款项目（编号：GZY-KJS-2019-002）：推进学术传承项目和传承人试点工作；负责人：田宁；广东省中医药局面上项目（编号：20222036）：热敏灸对早发性卵巢功能不全患者抗苗勒管激素（AMH）及抑制素B（INHB）的影响；负责人：曹淑华